Memorial Sloan Kettering Cancer Center;MASSACHUSETTS INSTITUTE OF TECHNOLOGY
发明人:
CHEAL, Sarah M.,XU, Hong,LARSON, Steven M.,CHEUNG, Nai-Kong,WITTRUP, Karl Dane
申请号：
EP16749705
公开号：
EP3256164A4
申请日:
2016.02.09
申请国别(地区):
EP
年份:
2018
代理人:
摘要：
Described herein are multi-specific binding agents that bind A33 and 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid. Also provided herein are methods of using multi-specific binding agents or compositions thereof for the detection, prevention, and/or therapeutic treatment of diseases characterized by expression of the A33 glycoprotein antigen, in particular, colorectal cancer.
