THE GENERAL HOSPITAL CORPORATION;PRANA BIOTECHNOLOGY LIMITED
发明人:
ASHLEY BUSH,ROBERT CHERNY,RUDOLPH EMILE TANZI
申请号：
HK09109775.3
公开号：
HK1131745B
申请日:
2009.10.22
申请国别(地区):
HK
年份:
2013
代理人:
摘要：
This invention relates to methods and compositions for the treatment or alleviation of Alzheimer's disease and of other conditions related to abnormal protein aggregation. In particular, the invention relates to methods and compositions for the immunotherapy of Alzheimer's disease, Parkinson's disease, and cataract. In one aspect the invention provides a method of prophylaxis, treatment or alleviation of a condition characterized by pathological aggregation and accumulation of a specific protein associated with an immunizing-effective dose of one or more tyrosine cross-linked compounds, and optionally also comprising copper ions complexed to the compound. Alternatively passive immunization against a tyrosine cross-linked compound may be used. Prophylactic or therapeutic compositions and diagnostic methods are also disclosed and claimed.
