The invention disclosed herein relates to a sampling cannula (10) for use in bone marrow biopsy procedures having structural features which facilitate sample retention within the device. In particular, the sampling cannula (10) comprises an open trough-like portion (13), wherein the trough-like portion (13) comprises at least one wall opening (16) located proximal to the distal end in combination with an interior surface (14) comprising a friction-enhancing surface texture (adapted to facilitate sample retention. The invention further provides for a bone marrow biopsy system comprising an outer cannula having a sharpened distal tip (15), a sampling cannula having a distal trough portion (13) in which the interior surface of the sampling cannula (14) is exposed, at least one wall opening located within the tough portion (13) located proximal to the distal tip of the sampling cannula, a friction-enhancing surface texture on at least a portion of the interior surface of the trough portion, wherein the sampling cannula is adapted to be inserted into an outer cannula (20), and to server a sample from the sampling site by rotational motion of the sampling cannula, and a stylet (30) structured to be removably inserted into the outer cannula (20). The bone biopsy system can further include and ejector rod for expelling the retained sample from the sampling cannula.Linvention porte sur un procédé sur une canule (10) de prélèvement déchantillons de moelle osseuse par biopsie, présentant des caractéristiques structurelles facilitant le rétention de léchantillon dans le dispositif. Ladite canule (10) présente en particulier une partie en tranchée ouverte (13) comportant au moins une ouverture pariétale (16) proximale de lextrémité distale combinée à une surface intérieure (14) texturée favorisant le frottement et conçue pour faciliter la rétention de léchantillon. Le système de biopsie comporte: une canule extérieure à extrémité distale (15) pointue, une canule de prélèvement p
