The present invention relates to a Lactuca sativa seed designated 41-106 RZ, which exhibits resistance to downy mildew (Bremia lactucae) races Bl:1-28, Ca-I to Ca-VIII, and strain FR10.021, currant-lettuce aphid (Nasonovia ribisnigri), lettuce mosaic virus (LMV), and to corky root rot (Sphingomonas suberifaciens), as well as broad base leaves. The present invention also relates to a Lactuca sativa plant produced by growing the 41-106 RZ seed. The invention further relates to methods for producing the lettuce cultivar, represented by lettuce variety 41-106 RZ.
