A wearable device having active feedback characteristics for physiological nursing, and a system and a method thereof are provided. A physiological sensing device is configured to sense a physiological sensing signal of a wearer, and the wearable device actively applies a preset functional response corresponding to the wearer when the physiological sensing signal is not within a safe range to enable the physiological sensing signal returning to a stable state. Disclosed actively and determinedly provides an instant response which enables the wearers physiological condition being controlled in a relative stable state, providing a pretreatment in no time to wait the follow-up aid, or deciding to do other treatments independently.