A method for producing drug-loaded polymeric nanoparticles, which includes the steps of: (a) preparing a first solution by dissolving a drug in a polymerizable monomer (b) preparing a micellar solution by dissolving a surfactant and a water-soluble radical initiator in water (c) adding said first solution to said micellar solution for polymerizing said polymerizable monomer, obtaining a dispersion of drug-loaded polymeric nanoparticles, the drug-loaded polymeric nanoparticles have a controlled size with average diameter smaller than 50 nm and (d) evaporating residual polymerizable monomer from the dispersion of drug-loaded polymeric nanoparticles.
