A garment for a human lower extremity with variable elasticity in the toe, heel and body of the garment is provided. A band of decreased elasticity is incorporated into the body of the sock extending from the toe area to the proximal end of the garment. A novel method for applying the sock includes twisting the garment, which results in providing targeted neuromuscular stimulation by the band to the location on the human lower extremity that the user positions the band over, thus improving alignment, gait, balance, circulation, and decreasing swelling and injury. Twisting of the garment also selectively increases a level of compression applied by the garment at said location relative to a level of pressure applied at adjacent locations. The location of the band and amount of compression generated by the garment is customizable by the wearer, depending upon the degree of twist chosen by the wearer.
