PROBLEM TO BE SOLVED: To provide a powdered drug spraying device that can spray and diffuse powdered drug without using an inconvenient medium such as gas or a solvent, eliminates the need for dissolving the drug in a solvent, eliminates the need for applying heat for diffusion, eliminates the need for a fixing power supply, and is portable and simple.SOLUTION: A powdered drug spraying device 1 includes: a bag 41 covered on an upper end opening part 13 of a container body 11 and receiving a gas generating agent 43 a cylindrical breaking member 31 held by a cylindrical guide member 21 attached to the upper part of a container body 11, and provided with a tip blade 37 breaking the bag 41 and making the gas generating agent 43 fall into water in the container body 11 a cylinder part 51 disposed inside the cylindrical breaking member 31, and having both opening ends capable of bringing the inside of the container body 11 into communication with the outside thereof a piston 61 hermetically sliding to a lower side slide inner circumferential wall 53 of the cylinder part 51, and having a gap to the upper side enlarged diameter inner circumferential wall 55 and powdered drug 30 stored in the cylinder part 51.