Kerns S. Jordan,Wen Norman,Lucchesi Carolina,Hinojosa Christopher David,Fraser Jacob,Hamilton Geraldine,Vatine Gad,Sances Samuel,Svendsen Clive,Levner Daniel,Sareen Dhruv
申请号:
US201815955335
公开号:
US2018298331(A1)
申请日:
2018.04.17
申请国别(地区):
美国
年份:
2018
代理人:
摘要:
The invention relates to culturing brain endothelial cells, and optionally astrocytes and neurons in a fluidic device under conditions whereby the cells mimic the structure and function of the blood brain barrier. Culture of such cells in a microfluidic device, whether alone or in combination with other cells, drives maturation and/or differentiation further than existing systems.