An over-the-counter (OTC) regulated therapeutic composition for self-medication use for application to wounds having a potential pathogen load, in which the composition comprises a tissue penetration enhancer comprising a Class I pharmaceutical incipient； a pharmaceutical antibiotic agent in a dosing suitable for use in an OTC listing； a hygroscopic carrier agent comprising a Class I pharmaceutical incipient suitable for mixing in solution with the tissue penetration enhancer and the antibiotic agent； and wherein the activity/water (AW) measurement of the composition is less than the Aw measurement for a target pathogen in a tissue wound.
