In order to effectively control ion channels of cells a signal (100) is suggested which comprises a first pulse sequence bundle (12a) and a second pulse sequence bundle (12b), each comprising at least two pulse sequences (11a, 11b, 11c, 11d, 11e, 11f), wherein each pulse sequence (11a, 11b, 11c, 11d, 11e, 11f) comprises at least one electromagnetic pulse (10a, 10b, 10c, 10d 10e, 10f). The signal (100) comprises a pulse sequence distance (13a, 13b, 13c) between adjacent pulse sequences (11a, 11b, 11c, 11d, 11e, 11f), wherein the signal (100) comprises a first pair (14a) of adjacent pulse sequences (11a, 11b, 11c, 11d, 11e, 11f) and a second pair of adjacent pulse sequences (11a, 11b, 11c, 11d, 11e, 11f), each comprising two pulse sequences (11a, 11b, 11c, 11d, 11e, 11f), wherein the signal (100) comprises the same pulse sequence distance between the adjacent pulse sequences (11a, 11b) of the first pair (14a) of pulse sequences (11a, 11b, 11c, 11d, 11e, 11f) and between the adjacent pulse sequences (11d, 11e) of the second pair of pulse sequences (11a, 11b, 11c, 11d, 11e, 11f).
