#$%^&*AU2019216697A120190905.pdf#####Il: sxd nterwoven NRPortbl DCC SXD 15605318_ .docx-30/08/2017 ABSTRACT (L4-Ar)p A RI L0 R5 2 N RO-y/Z N L ' L2 N Z X-R9 RI-Y fOr R2 R2 n R R4 L3a A (L4-Ar), The present application provides for a compound of Formula I, or a pharmaceutically acceptable salt, solvate, and/or ester thereof, compositions containing such compounds, therapeutic methods that include the administration of such compounds, and therapeutic methods and include the administration of such compounds with at least one additional therapeutic agent.