Иващенко Александр Васильевич (RU),Демин Александр Викторович (RU)
申请号：
RU2011132497/04
公开号：
RU2011132497A
申请日:
2011.08.03
申请国别(地区):
RU
年份:
2013
代理人:
摘要：
1. The compound 2-amino-2- [2- (4-octylphenyl) ethyl] propane-1,3-diol or a pharmaceutically acceptable salt thereof, having the property modulator or agonist S1P retseptorov.2. A pharmaceutical composition comprising a modulator or a S1P receptor agonist 2-amino-2- [2- (4-octylphenyl) ethyl] propane-1,3-diol or a pharmaceutically acceptable salt, edible vegetable oil and optionally containing antioksidant.3. A pharmaceutical composition according to claim 2, characterized in that the edible oil comprises an oil selected from avocado oil, apricot kernel, peanut, grape, cherry, walnut, wheat oil, cacao oil, cedar, coconut, hemp, corn, sesame, linseed, almond, sea buckthorn, olive, palm, sunflower, rapeseed, rice, soybean, cotton or pumpkin masla.4. A pharmaceutical composition according to claim 2, characterized in that the antioxidant may be selected from alpha-tocopherol acetate or butilgidroksianizola.5. A pharmaceutical composition according to any one of claims 2-4 for oral vvedeniya.6. A medicament in the form of a pharmaceutically acceptable capsule containing a pharmaceutical composition according to any one pp.2-4.7. A medicament according to claim 6 in the form of gelatinous kapsuly.8. A method of treatment of the subject in need of suppression of the immune system, consisting in the fact that the subject is administered an effective amount of the pharmaceutical composition according to any one of claims 2-4 or medicament according to claim 6 or 7.9. A method according to claim 8 for treating a subject in need of treatment of multiple sclerosis.1. Соединение 2-амино-2-[2-(4-октилфенил)этил]пропан-1,3-диол или его фармацевтически приемлемая соль, обладающее свойством модулятора или агониста S1P рецепторов.2. Фармацевтическая композиция, включающая в качестве модулятора или агониста рецептора S1P 2-амино-2-[2-(4-октилфенил)этил]пропан-1,3-диол или его фармацевтически приемлемую соль, пищевое растительное масло и необязательно содержащая антиоксидант.3. Фармац
