The Board of Regents; The University of Texas System
发明人:
Jian Yang
申请号：
US14146272
公开号：
US20140193356A1
申请日:
2014.01.02
申请国别(地区):
US
年份:
2014
代理人:
摘要：
In one aspect, methods of promoting bone growth are described herein. In some embodiments, a method of promoting bone growth described herein comprises promoting cell differentiation or phenotype progression in a population of bone cells by providing a citrate-presenting composition to the population of bone cells. In some embodiments, the citrate-presenting composition is provided to the bone cells at a first stage of cell development selected to obtain a first cell differentiation or phenotype progression. Additionally, in some cases, a second citrate-presenting composition is further provided to the bone cells at a second stage of cell development selected to obtain a second cell differentiation or phenotype progression.
