Compositions and methods for inhibiting gastric acid secretion using PPI in combination with small dicarboxylic acid derivatives

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专利权人:

ベクタ・リミテッド

发明人:

マラシュ、マイケル,コスタディノブ、アレクセイ,アトロト、タル

申请号：

JP2009521362

公开号：

JP5474541B2

申请日:

2007.07.19

申请国别(地区):

JP

年份:

2014

代理人:

摘要：

The present invention is related to novel oral compositions comprising an irreversible gastric H+/K+-ATPase proton pump inhibitor (PPI) as a gastric acid secretion inhibitor and one or more aliphatic carboxylic acid derivative molecules which activate parietal cells, wherein the derivatives possess delayed or sustained enhancement effect on the PPI activity compared to the non-derivatized acid molecules. The present invention further relates to a method of using such compositions to reduce gastric acid secretion in a mammal.

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中国工程科技知识中心

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http://www.ckcest.cn/home/