Robert E. W. Hancock,Olga M. Pena Serrato,David G. Hancock,John Boyd
申请号：
US16279788
公开号：
US20200032321A1
申请日:
2019.02.19
申请国别(地区):
US
年份:
2020
代理人:
摘要：
A method of diagnosing severe sepsis prior to definitive clinical diagnosis. A pattern of gene expression that correlates strongly with a future diagnosis of severe sepsis and organ failure was identified in patients who had their blood drawn at first clinical presentation. The methods comprise identifying a pattern of two or more polynucleotides, whereby the altered expression of these polynucleotides correlates with prospective and actual sepsis. Also methods of identifying agents for treating sepsis based on the characteristics of this gene expression pattern are provided.
