According to one aspect, systems and processes for resampling data for 3D printing from voxels are provided. In an exemplary process, a native resolution dataset representing an object to be printed is received. A first slice of data from the native resolution dataset is up-sampled, and first up-sampled data is communicated to a 3D printer for printing. Next, a second slice of data from the native resolution dataset is up-sampled, and second up-sampled data is communicated to the 3D printer for printing. Furthermore, the second slice of data may be up-sampled subsequent to the up-sampling of the first slice of data or subsequent to the communicating of the first up-sampled data to the 3D printer.