The present invention relates to a composition for preventing or treating lipid-related metabolic diseases. The composition according to the present invention comprises D-psicose as an active ingredient. D-psicose has the ability to inhibit lipid absorption in the small intestine and considerably increase lipid levels in feces. Due to its ability, D-psicose is effective in inhibiting the formation of body fat. In addition, D-psicose reduces body weight, body fat mass, and plasma lipid to normal levels to normalize body weight, body fat mass, and plasma lipid profiles. Due to these advantages, D-psicose is expected to find application in pharmaceutical drugs, health functional foods, and functional foods suitable for preventing and/or treating lipid-related metabolic diseases.
