PHARMACEUTICAL COMPOSITIONS COMPRISING 4-(6Br,10aS)-3-METHYL-2,3,6b,9,10,10a-HEXAHYDRO-lH,7H-PYRIDO[3',4':4,5]PYRROLO[l,2,3-de] QUIN OX ALIN - 8 - YL) -1 -(4-FLU OROPHEN YL) -BUT ANE-1 - ONE AND METHODS OF TREATING CONDITIONS OF THE CENTRAL NERVOUS SYSTEM
Peng LI,Qiang ZHANG,Robert DAVIS,Lawrence P. WENNOGLE
申请号:
US16591178
公开号:
US20200102310A1
申请日:
2019.10.02
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The invention relates to pharmaceutical compositions comprising 4-((6bR,10aS)-3-methyl -2,3,6b,9,10,10a-hexahydro-1H,7H-pyrido[3′;,4′;:4,5]pyrrolo[1,2,3-de]quinoxalin-8-yl)-1-(4 -fluorophenyl)-butan-1-one, and methods of use in the treatment of diseases involving 5-HT2A receptor, serotonin transporter (SERT) pathway and/or the dopamine D2 receptor pathway, and methods of treating conditions of the central nervous system therewith.