A computer implemented method for performing bone segmentation in imaging data of a section of a body structure is provided. The method includes: Obtaining the imaging data including a plurality of 2D images of the section of the body structure and performing a multiphase local-based hybrid level set segmentation on at least a subset of the plurality of 2D images by minimizing an energy functional including a local-based edge term and a local-based region term computed locally inside a local neighborhood centered at each pixel of each one of the 2D images on which the multiphase local-based hybrid level set segmentation is performed, the local neighborhood being defined by a Gaussian kernel whose size is determined by a scale parameter (σ).
