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Processes for the preparation of S1P1 receptor modulators and crystalline forms thereof
- 专利权人:
- Arena Pharmaceuticals; Inc.
- 发明人:
- JONES, Robert M.,BUZARD, Daniel J.,GHARBAOUI, Tawfik,JOHNSON, Benjamin R.,KASEM, Michelle,SCHRADER, Thomas O.,STIRN, Scott
- 申请号:
- ES11707330
- 公开号:
- ES2558087T3
- 申请日:
- 2011.03.02
- 申请国别(地区):
- ES
- 年份:
- 2016
- 代理人:
- 摘要:
- A salt selected from: L-lysine salt of (R) -2- (9-chloro-7- (4-isopropoxy-3- (trifluoromethyl) benzyloxy) -2,3-dihydro-1H-pyrrolo [1, 2- a] indole-1-yl) acetic; Sodium salt of (R) -2- (9-Chloro-7- (4-isopropoxy-3- (trifluoromethyl) benzyloxy) -2,3-dihydro-1H-pyrrolo [1,2-a] indole-1 -il) acetic; Sodium salt hydrate of (R) -2- (9-Chloro-7- (4-isopropoxy-3- (trifluoromethyl) benzyloxy) -2,3-dihydro-1H-pyrrolo [1,2-a] indole-1-yl) acetic; Ethylene diamine (R) -2- (9-chloro-7- (4-isopropoxy-3- (trifluoromethyl) benzyloxy) -2,3-dihydro-1H-pyrrolo [1,2-a] indole-1- salt hydrate il) acetic; (R) -2- (9-Chloro-7- (4-isopropoxy-3- (trifluoromethyl) benzyloxy) -2,3-dihydro-2-amino-2-hydroxymethyl-propane-1,3-diol salt -1H-pyrrolo [1,2-a] indole-1-yl) acetic acid; L-arginine salt of (R) -2- (9-chloro-7- (4-isopropoxy-3- (trifluoromethyl) benzyloxy) -2,3-dihydro-1H-pyrrolo [1,2- a] indole -1-yl) acetic; Zinc salt of (R) -2- (9-Chloro-7- (4-isopropoxy-3- (trifluoromethyl) benzyloxy) -2,3-dihydro-1H-pyrrolo [1,2-a] indole-1 - il) acetic; Calcium salt of (R) -2- (9-Chloro-7- (isopropoxy-3- (trifluoromethyl) benzyloxy) -2,3-dihydro-1H-pyrrolo [1,2-a] indole-1-yl )acetic; (R) -2- (9-Chloro-7- (4-isopropoxy-3- (trifluoromethyl) benzyloxy) -2,3-dihydro-1H-pyrrolo [1,2-a] indole-1 N-methylglucamine salt -il) acetic; (R) -2- (9-Chloro-7- (4-isopropoxy-3- (trifluoromethyl) benzyloxy) -2,3-dihydro-1H-pyrrolo [1,2- a] indole-1 potassium salt -il) acetic; and Magnesium salt of (R) -2- (9-chloro-7- (4-isopropoxy-3- (trifluoromethyl) benzyloxy) -2,3-dihydro-1H-pyrrolo [1,2- a] indole- 1-yl) acetic.Una sal seleccionada entre: Sal de L-lisina del ácido (R)-2-(9-cloro-7-(4-isopropoxi-3-(trifluorometil)benciloxi)-2,3-dihidro-1H-pirrolo[1,2- a]indol-1-il)acético; Sal de sodio del ácido (R)-2-(9-cloro-7-(4-isopropoxi-3-(trifluorometil)benciloxi)-2,3-dihidro-1H-pirrolo[1,2-a]indol- 1-il)acético; Hidrato de la sal de sodio del ácido (R)-2-(9-cloro-7-(4-isopropoxi-3-(trifluorometil)benciloxi)-2,3-dihid
- 来源网站:
- 中国工程科技知识中心
- 来源网址:
- http://www.ckcest.cn/home/