The invention relates to a prophylactic article with a carrier element, which comprises at least in part a natural or synthetic elastomer, and with a combination of active substances that is contained in microcapsules, wherein the microcapsules are arranged at least in part in and/or on the carrier element. The combination of active substances contains at least one skin care agent, at least one preservative, at least one odor-inhibiting agent and at least one antioxidant.