Compounds derived from piperazin - pyridin - biphenyl substituted imidazole - pyrrolidines, inhibitors of the replication of the hepatitis C virus (HCV)； Pharmaceutical composition that comprises； a process for preparing a Compound, method for treating hcv infection of the virus and use for treating； Hcv infection of the virus.
LONG DANIEL D,MCKINNEL ROBERT MURRAY,JIANG LAN,LOO MANDY,LEPACK KASSANDRA,VAN ORDEN LORI JEAN,OGAWA GARIN,HUANG XIAOJUN,ZHANG WEIJIANG
申请号：
CL2014001110
公开号：
CL2014001110A1
申请日:
2014.04.29
申请国别(地区):
CL
年份:
2014
代理人:
摘要：
The invention provides compounds of formula (I): wherein the variables are defined in the specification, or a pharmaceutically-acceptable salt thereof, that are inhibitors of replication of the hepatitis C virus. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat hepatitis C viral infections, and processes and intermediates useful for preparing such compounds.Compuestos derivados de piperazin-piridin-bifenil-imidazol-pirrolidinas sustituidas, composición farmacéutica que los comprende； proceso para preparar un compuesto； compuesto intermediario y uso de los compuestos en la preparación de un medicamento útil para tratar una infección del virus de la hepatitis C en un mamífero.
