PROBLEM TO BE SOLVED: To provide a new parakeratosis-suppressing agent and a new pore shrinking agent having a parakeratosis-suppressing function, a pore shrinking function, etc., and to provide external skin compositions for skin having the functions.SOLUTION: This parakeratosis-suppressing agent and the pore shrinking agent are each composed of one, two, or more kinds of compounds selected from a group comprising a glycine derivative, an aminodicarboxylic acid derivative, an acylaminodicarboxylic acid derivative, a pyrrolidinecarboxylic acid derivative, a piperidinecarboxylic acid derivative, a hexamethyleneiminecarboxylic acid derivative, a &beta-alanine derivative, and a salt of each of the derivatives. A parakeratosis-suppressing external preparation for skin and a pore shrinking external preparation for skin contain the parakeratosis-suppressing agent and the pore shrinking agent, respectively.COPYRIGHT: (C)2005,JPO&NCIPI【課題】不全角化抑制、毛穴縮小等の機能を有する新規な不全角化抑制剤、毛穴縮小剤を提供すること、さらに前記機能を有する皮膚外用組成物を提供すること。【解決手段】グリシン誘導体、アミノジカルボン酸誘導体、アシルアミノジカルボン酸誘導体、ピロリジンカルボン酸誘導体、ピペリジンカルボン酸誘導体、ヘキサメチレンイミンカルボン酸誘導体及びβ-アラニン誘導体並びに前記各誘導体の塩からなる群から選ばれる化合物の1種又は2種以上からなる不全角化抑制剤、毛穴縮小剤。さらに、前記不全角化抑制剤、毛穴縮小剤を含有する不全角化抑制用皮膚外用剤、毛穴縮小用皮膚外用剤。【選択図】なし
