Blankenship, John W.,Tan, Philip,Natarajan, Sateesh Kumar,Algate, Paul A.,Chenault, Ruth A.
申请号:
AU2010343056
公开号:
AU2010343056A1
申请日:
2010.12.29
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
This disclosure provides immunoglobulin binding molecules that specifically bind to human macrophage stimulating receptor (MST1 R, also referred to herein as recepteur d'origine Nantaise or RON), including antibodies and monospecific and multispecific single chain binding proteins having one or more other domains, such as one or more antibody constant region domains. Also provided are therapeutic applications of such binding proteins, such as for the treatment of cancer and inflammatory disorders.