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A NASAL PHARMACEUTICAL FORMULATION
专利权人:
发明人:
CHAUDRY IMTIAZ
申请号:
IN1850/KOLNP/2005
公开号:
IN251492B
申请日:
申请国别(地区):
IN
年份:
2012
代理人:
摘要:
Nasal pharmaceutical formulations comprising a drug substance having a specific particle size distribution profile aredisclosed herein. Such profile provides increased bioavailability, increased efficacy or prolonged therapeutic effect of the drug substancewhen administered intranasally. The formulations of the present invention may comprise one or more corticosteroids havinga specific particle size distribution profile. In a preferred embodiment, the corticosteroid is beclomethasone or a pharmaceuticallyacceptable derivative thereof for the treatment of one or more symptoms of rhinitis. Preferably, the drug substance is beclomethasonedipropionate. The formulations herein may be provided as an aqueous suspension suitable for inhalation via the intranasal route
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