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ANTISENSE MODULATION OF FACTOR 7 EXPRESSION
专利权人:
INC.;ISIS PHARMACEUTICALS
发明人:
FREIER, SUSAN, M,MONIA, BRETT, P,ZHANG, HONG,CROSBY, JEFFREY, R,ZHAO, CHENGUANG
申请号:
NZ58525008
公开号:
NZ585250A
申请日:
2008.11.05
申请国别(地区):
NZ
年份:
2012
代理人:
摘要:
Disclosed is a compound comprising an oligonucleotide consisting of 12 to 30 linked nucleosides targeted to a Factor 7 nucleic acid, wherein the oligonucleotide has a sequence that is least 90% complementary to SEQ ID NO: 1. Also disclosed is the use of the said compound in the manufacture of a medicament for the treatment of a disease or condition associated with Factor 7 by administering to the animal a therapeutically effective amount of the compound so that expression of Factor 7 is inhibited.
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