KOSKELAINEN, TUULA,LINNANEN, TERO,MINKKILA, ANNA,MAKELA, MIKKO,POHJAKALLIO, ANTTI
申请号：
CA2868611
公开号：
CA2868611A1
申请日:
2013.03.28
申请国别(地区):
CA
年份:
2013
代理人:
摘要：
The present invention relates to pharmacologically active isochroman andisothiochromanderivatives, or pharmaceutically acceptable salts thereof, as well as topharmaceuticalcompositions comprising them and to their use as alpha2 adrenoceptor agonists,especiallyas alpha2A agonists, such as for the treatment of delirium, hyperactivedelirium, insomnia,ADHD, benzodiazepine or alcohol or opioid or tobacco withdrawal, prematureejaculation,hypertension, tachycardia, restless leg syndrome, muscular spasticity, hotflashes, anxiety,post traumatic stress disorder, pain, chronic pelvic pain syndrome,breakthrough cancer pain,or a condition wherein sedation or analgesia is needed.
