A prosthetic valve comprising a conical shaped member comprising an extracellular matrix (ECM) composition, the conical shaped member comprising a sheet member having a plurality of slit regions that are configured to open during expansion of the sheet member that is induced by positive fluid flow through the sheet member and close during contraction of the sheet member that is induced by negative fluid flow through the sheet member.Une valve prothétique conique comprend une matrice extracellulaire (ECM) et une feuille ayant plusieurs fentes. Un débit positif de liquides à travers la feuille provoque l'expansion de la feuille et l'ouverture des fentes. Alors qu'un débit négatif ferme les fentes et provoque une contraction de la feuille.
