A chemically foaming hemostat may use a liquid gel, a dried gel, a dry powder, or a solid “plug” like medium including a foaming agent to stop bleeding. The hemostat also may introduce pharmaceuticals and/or other compounds into a wound to control/mitigate shock, calm the patient, administer antibiotics, administer anti-sepsis compounds, control infection, control sepsis, and/or mitigate pain. No foreign matter need be introduced in connection with use of a chemically foaming hemostat. This eliminates the need to surgically remove introduced foreign matter at a later time. Use of a chemically foaming hemostat also may reduce the likelihood of trauma that sometimes occurs when foreign matter is left in place inside a wound.