This invention relates to deuterated analogs of etifoxine of Formula 1, solvates, prodrugs, and pharmaceutically acceptable salts thereof, as well as to methods for their preparation and use, and to pharmaceutical compositions. Briefly, this invention is generally directed to deuterated analogs of etifoxine as well as to methods for their preparation and use, and to pharmaceutical compositions containing the same.Esta invención se refiere a análogos deuterados de etifoxina de la Fórmula I, solvatos, profármacos, y sales farmacéuticamente aceptables de estos, así como a métodos para su preparación y uso, y a composiciones farmacéuticas. (Ver fórmula).