PROBLEM TO BE SOLVED: To provide a preventive or therapeutic agent of cancer caused by a mechanism different from cell proliferation inhibition.SOLUTION: A preventive or therapeutic agent of cancer which contains peptide which consists of amino acid sequence described in sequence number 1 or a derivative thereof, or peptide which consists amino acid sequence in which 1 or a plurality of amino acid are deleted, substituted, or added in the amino acid sequence described in sequence number 1 and which has microtubular binding activity, or a derivative thereof, as an active ingredient.SELECTED DRAWING: NoneCOPYRIGHT: (C)2018,JPO&INPIT【課題】細胞増殖阻害とは異なるメカニズムによる癌の予防又は治療剤を提供する。【解決手段】配列番号1に記載のアミノ酸配列からなるペプチド若しくはその誘導体、又は配列番号1に記載のアミノ酸配列において1若しくは複数個のアミノ酸が欠失、置換若しくは付加されたアミノ酸配列からなり、かつ微小管結合活性を有するペプチド若しくはその誘導体、を有効成分として含有する癌の予防又は治療剤。【選択図】なし