A fluidized bed reactor, comprising a vertical body (1) with an injector (3) for a solution to be treated at its lower end, an input system (5) for a metal reagent, a solution agitator and an upper outlet (4), has a finishing compartment (6) with divergent walls at the upper end of the reactor body containing ultrasound emitters (7) that are immersed in the solution. The reactor body is cylindrical in shape and is subdivided into a number of parallel vertical compartments (11) by cylindrical or flat walls, while the injector is connected to a chamber (2) containing balls (12) of an inert material such as aluminium, plastic or glass.Anvendelse av en immunogen blanding omfattende VZV gE, eller immunogent fragment derav, og en TH-1 adjuvans ved fremstilling av et medikament for forebygging eller forbedring av helvetesild og/eller post-herpetisk neuralgi. Blandinger omfattende et trunkert VZV gE-antigen og en adjuvans inneholdende QS21, kolesterol og 3D MPL omfattes også.
