Jun Ouchi,Shunji Kunori,Yozo Kojima,Katsumi Shinoda,Katsutoshi Sasaki,Shiro Shirakura
申请号：
US12994923
公开号：
US08865731B2
申请日:
2009.05.29
申请国别(地区):
US
年份:
2014
代理人:
摘要：
Provided are: an agent for suppressing an undesirable effect of an opioid-type analgesic (opioid), which comprises a compound having adenosine A2A receptor antagonistic activity or a pharmaceutically acceptable salt thereof as an active ingredient； the agent for suppressing an undesirable effect of an opioid-type analgesic (opioid), wherein the undesirable effect of the opioid-type analgesic (opioid) is analgesic tolerance or constipation； the agent for suppressing an undesirable effect of an opioid-type analgesic (opioid), wherein the undesirable effect of the opioid-type analgesic (opioid) is analgesic tolerance； and the like.
