WEBER, RICHARD,FENG, XIAO,FOORD, ORIT,GREEN, LARRY,GUDAS, JEAN,KEYT, BRUCE,LIU, YING,RAYA, ROBERT,YANG, XIAO DONG,CORVALAN, JOSE,JIA, XIAO-CHI,KANG, JASPAL,KLAKAMP, SCOTT L.,SU, QIAOJUAN JANE,FOLTZ, I
申请号:
CA2530285
公开号:
CA2530285C
申请日:
2004.06.25
申请国别(地区):
CA
年份:
2019
代理人:
摘要:
The present invention relates to novel antibodies, particularly antibodiesdirected against deletion mutants of epidermalgrowth factor receptor and particularly to the type III deletion mutant,EGFRvIII. The invention also relates to human monoclonalantibodies directed against deletion mutants of epidermal growth factorreceptor and particularly to EGFRvIII. Diagnostic andtherapeutic formulations of such antibodies, and immunoconjugates thereof, arealso provided.