1. A monoclonal antibody that binds to the extracellular domain of human tyrosine phosphatase σ receptor type (human PTPRS), or a fragment including its antigen-binding region. A monoclonal antibody or fragment, including its antigen binding region according to claim 1, which binds to a plasmacytoid dendritic cell. Monoclonal antibody produced by hybridoma 9H5-4, which was deposited as accession number FERM ABP-11356, hybridoma 10F7-38, which was deposited as accession number FERM ABP-11357, hybridoma 13G5-52, which was deposited as access number No. FERM ABP-11358, hybridoma 13G5-57, which was deposited as access number No. FERM ABP-11359, hybridoma 14A8-85, which was deposited as access number No. FERM ABP-11360, hybridoma 22H8-84, which was deposited as access number No. FERM ABP-11361, hybridoma 49F2-30, which yla deposited as an access number № FERM ABP-11362, or hybridoma 55E7-79, which was deposited with the access number as № FERM ABP-11363, or a fragment comprising its antigen binding oblast.4. A hybridoma that produces any of the monoclonal antibodies of claim 1 or 2.5. Monoclonal antibody produced by hybridoma 9H5-4, which was deposited as accession number FERM ABP-11356, hybridoma 10F7-38, which was deposited as accession number FERM ABP-11357, hybridoma 13G5-52, which was deposited as number access number FERM ABP-11358, hybridoma 13G5-57, which was deposited as access number No. FERM ABP-11359, hybridoma 14A8-85, which was deposited as access number No. FERM ABP-11360, hybridoma 22H8-84, which would �1. Моноклональное антитело, которое связывается с внеклеточным доменом протеинтирозинфосфатазы σ рецепторного типа человека (PTPRS человека), или фрагмент, включающий его антигенсвязывающую область.2. Моноклональное антитело или фрагмент, включающий его антигенсвязывающую область по п. 1, которые связываются с плазмацитоидной дендритной клеткой.3. Моноклональное антитело, продуцируемое гибридомой 9H5-4, которая была депонирована в качестве номера доступа №