The present invention relates to: - a composition, in particular, of sebum artificial comprising several waxes. - the use of the said cosmetic composition comprising the sebum artificial comprising several waxes to treat dry hair and / or dry skin and / or sensitive and / or burnt. - use of said composition for mimicking the sebum human - the use of a cosmetic composition comprising the sebum artificial comprising several waxes for the preparation of a skin equivalent comprising an equivalent of sebum - a skin equivalent comprising an equivalent of sebum - as well as the use of a skin equivalent comprising an equivalent of sebum.