The disclosure relates to an oral care composition an effective amount of at least one C1-4 (optionally hydroxylated) alkyl glycoside, e.g., β-methyl-D-galactoside, wherein the glycoside promotes the growth of beneficial endogenous bacteria and negatively affects the growth of endogenous pathogenic strains of bacteria. The disclosure also relates to methods of use, methods of screening, and methods of manufacture of said oral care compositions.本發明係關於包含有效量之至少一種C1-4(視需要羥基化的)烷基糖苷(例如β-甲基-D-半乳糖苷)的口腔護理組成物，其中該糖苷能促進有益之內源性細菌生長並負向的影響內源性病原菌之菌株生長。本發明亦關於該口腔保健組成物之使用方法、篩選方法，以及製造方法。
