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Cyclic azaindole-3-carboxamides, their use as their preparation and pharmaceutical
专利权人:
サノフイ
发明人:
ヘニング・シュタインハーゲン,ボード・シャイパー,ハンス・マッター,ガリ・ムコール
申请号:
JP2010544614
公开号:
JP5727793B2
申请日:
2009.01.17
申请国别(地区):
JP
年份:
2015
代理人:
摘要:
The present invention relates to cyclic azaindole-3-carboxamides of the formula I, wherein A, R, R10, R20, R30, R40, Y1, Y2, Y3, Y4, n, p and q have the meanings indicated in the claims, which are valuable pharmaceutical active compounds. Specifically, they inhibit the enzyme renin and modulate the activity of the renin-angiotensin system, and are useful for the treatment of diseases such as hypertension, for example. The invention furthermore relates to processes for the preparation of the compounds of the formula I, their use and pharmaceutical compositions comprising them.
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