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Aromatic compounds for suppressing the generation of collagen
专利权人:
Takashi Nakagawa;Hideki T;Hironori Tsutsui;Nobuaki Ito;Kenji Watanabe;Takuya Shitsuta;Kuninori Tai;Michinori Tanaka;Noriaki Takemura;Hitoshi Nagao;Shuji Matsumura;Keizo Kan;Hideaki Satou;Tae Fukushima
发明人:
Tae Fukushima,Shuji Matsumura,Noriaki Takemura,Hideaki Satou,Nobuaki Ito,Takuya Shitsuta,Hironori Tsutsui,Michinori Tanaka,Keizo Kan,Hitoshi Nagao,Kenji Watanabe,Kuninori Tai,Takashi Nakagawa,Hideki T
申请号:
US11659689
公开号:
US08188277B2
申请日:
2005.08.03
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention provides a novel compound, which has an excellent effect of suppressing the generation of collagen and less side effects, with being excellent in terms of safety. The compound of the present invention is represented by the following general formula (1):[wherein X1 represents a nitrogen atom or a group —CH═; R1 represents a group —Z—R6, wherein Z represents a group —CO—, a group —CH(OH)—, or the like, and R6 represents a 5- to 15-membered monocyclic, dicyclic, or tricyclic, saturated or unsaturated heterocyclic group having 1 to 4 nitrogen atoms, oxygen atoms, or sulfur atoms; R2 represents a hydrogen atom, a halogen atom or a lower alkylene group; Y represents a group —O—, a group —CO—, a group —CH(OH)—, a lower alkylene group, or the like; and A represents a groupor the like, wherein R3 represents a hydrogen atom, a lower alkoxy group, or the like, p represents 1 or 2, and R4 represents an imidazolyl lower alkyl group or the like.
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