Gregory Hoffman;Zainab Jagani;Frank Peter Stegmeier;Craig Stephen Mickanin
发明人:
Zainab Jagani,Gregory Hoffman,Frank Peter Stegmeier,Craig Stephen Mickanin
申请号:
US14777211
公开号:
US09850543B2
申请日:
2014.03.12
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The invention provides methods of detecting cancer biomarkers, such as one or more SWI/SNF complex mutations, in order to determine a cancer subject's amenability to therapeutic treatment with a BRM inhibitor. Kits, methods of screening for candidate BRM inhibitors, and associated methods of treatment are also provided.