Anti-CDH3 antibody having high internalization capacity

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专利权人:

Keisuke Ishii

发明人:

Keisuke Ishii,Keiko Katsumi,Tadashi Matsuura,Yukio Sudo,Katsuyuki Mitomo,Katsushi Kouda

申请号：

US13882453

公开号：

US09328160B2

申请日:

2011.10.28

申请国别(地区):

US

年份:

2016

代理人:

摘要：

It is an object of the present invention to provide an anti-cadherin antibody having a high internalization capacity and provide an anti-cadherin antibody-drug conjugate that effectively kills cadherin-expressing cancer cells with the use of such antibody. The present invention provides an anti-cadherin antibody which recognizes a cadherin domain 1 (EC1) of cadherin and exhibits a high internalization capacity.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/