As a therapeutic agent for central nervous system disorders related to phosphoric acid 10, three triazole compounds are replaced by two alcohols. It also refers to the use of these compounds in the treatment of neurological and psychiatric disorders, such as schizophrenia, psychosis or Huntington's disease, as well as diseases related to muscle atrophy or matrix necrosis. 1. Claim 1: a formula compound (1),A is the rest of the formula (2) or (3)；R represents H or C₁₋₆ alkyl；R¹ is selected from the groups consisting of (CH₂) ₙ-haloalkyl C₁₋₄,1. Lease land No. c833218331 and 832626；cycloalkyl C₃₋₆,aryl C₆₋₁₀,1. There are 1 to 3 r74919 hydraulic tar and arilo without replacement or replacement；R2 was transferred from h, o-r, CN, O (ch8322or) 8345or, ochr (ch83228345or), Sr, so8322； R, s (o) r, n (R) 83222；C (O) N (R)Halogenated tar c83218323；O (CH₂) ₙ-haloalkyl C₁₋₃,O (CH) -cicloalquilo C(CH₂) ₙ-heterocycle C₅₋₁₀,1. Lease land No. c833218331 and 832626；y cicloalquilo C1. There are 1 to 3 r74911 grade asphalt, cyclopropyl and non positive cycles；Rᵃ is selected from the group consisting of: (i) halogen, (ii) hydroxyl, (iii) C₁₋₆ alkyl,(Iv) - (CH) O-R (v) (CH) -arilo C(vi) (CH₂) ₙ-heterocycle C₅₋₁₀,(Vii) O-haloalquilo C(Viii) CO R (ix) C (O) N (R)(X) (CH) C (O) R (xi) CN (xii) (CH) N (R)(Xiii) (CH) -cicloalquilo C(xiv) (CH₂) ₙ-haloalkyl C₁₋₃；N represents 0-4； or salt acceptable for the drug.Son compuestos de triazol sustituidos con alcoholes secundarios como agentes terapéuticos para el tratamiento de trastornos del sistema nervioso central asociados con la fosfodiesterasa 10 (PDE10). También se refiere al uso de dichos compuestos para tratar trastornos neurológicos y psiquiátricos, tales como esquizofrenia, psicosis o enfermedad de Huntington, y los asociados con la hipofunción del cuerpo estriado o la disfunción de los ganglios basales. Reivindicación 1: Un compuesto de fórmula (1), en la que: A representa un resto de fórmula (2) ó (3)； R representa H o alquilo C₁₋₆； R¹
