PURIFICATION OF VACCINIA VIRUS- AND RECOMBINANT VACCINIA VIRUS-BASED VACCINES

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专利权人:

BAVARIAN NORDIC A/S

发明人:

DJURUP, RENE,POST HANSEN, SARA

申请号：

NZ57896008

公开号：

NZ578960A

申请日:

2008.05.07

申请国别(地区):

NZ

年份:

2012

代理人:

摘要：

Disclosed is a method for the purification of biologically active Vaccinia virus comprising: i) loading a solid-phase matrix, to which a ligand is attached, with a Vaccinia virus contained in a liquid-phase culture, wherein the ligand is glucosamine glycan (GAG) or a GAG-like ligand ii) washing the matrix and iii) eluting the virus.

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