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強膜透明化による角膜移植材料調製方法
专利权人:
国立大学法人東北大学
发明人:
西田 幸二,田中 佑治,久保田 享
申请号:
JP2008141043
公开号:
JP5388090B2
申请日:
2008.05.29
申请国别(地区):
JP
年份:
2014
代理人:
摘要:

PROBLEM TO BE SOLVED: To provide a transplant material originated in the same species to be used for treating corneal damage.

SOLUTION: A method for making sclera transparent includes a (a) step for dehydrating sclera tissues isolated from an animal donor and a (b) step for applying crosslinking processing to the sclera tissues from the step (a), and the sclera tissues are made transparent by the method. The tissue is made transparent by using 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide hydrochloride (EDC), 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide hydrochloride/N-hydroxy succinimide (EDC/NHS), glutaraldehyde, or paraformaldehyde to apply the crosslinking processing by ultraviolet radiation.

COPYRIGHT: (C)2010,JPO&INPIT

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