THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY DEPARTMENT OF HEALTH AND HUMAN SERVICES
发明人:
KOCHENDERFER JAMES NOBLE
申请号:
NZ70036213
公开号:
NZ700362A
申请日:
2013.03.15
申请国别(地区):
NZ
年份:
2016
代理人:
摘要:
The invention provides an isolated and purified nucleic acid sequence encoding a chimeric antigen receptor (CAR) directed against B-cell Maturation Antigen (BCMA). The invention also provides host cells, such as T-cells or natural killer (NK) cells, expressing the CAR and methods for destroying multiple myeloma cells.