Methods of making medical devices are described. A method of making a medical device for delivering a bioactive includes preparing a suitable solution comprising the bioactive placing a vessel containing the solution over a substrate comprising a biocompatible foam and defining open cells initiating flow of the solution from the vessel and toward the substrate such that the solution exits the vessel and contacts the substrate and maintaining flow of the solution for an amount of time sufficient to achieve a desired volume of the solution within the substrate. Medical devices made by the methods are also described.
