Alpha7 nicotinic acetylcholine receptor modulators and uses thereof-i

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专利权人:

Merck Sharp & Dohme Corp.

发明人:

Harvey, Andrew,Avery, Thomas,Paul, Dharam,Ripper, Justin,Huff, Belinda,Singh, Rajinder,Schaeffer, Laurent,Joseph, Christophe,Morice, Christophe,Giethlen, Bruno

申请号：

AU2013299330

公开号：

AU2013299330B2

申请日:

2013.08.01

申请国别(地区):

AU

年份:

2018

代理人:

摘要：

The present invention relates to chemical compounds of formula (I), with the substituents as described in the specification, useful in the positive modulation of the alpha 7 nicotinic acetylcholine receptor (α7 nAChR). The invention also relates to the use of these compounds in the treatment or prevention of a broad range of diseases in which the positive modulation of α7 nAChR is advantageous, including neurodegenerative and neuropsychiatric diseases and also neuropathic pain and inflammatory diseases.

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中国工程科技知识中心

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http://www.ckcest.cn/home/