Nitya Nair,Lisa Blum,Ningguo Feng,William H. Robinson,Harry Greenberg,Mrinmoy Sanyal
申请号:
US15737634
公开号:
US20180155411A1
申请日:
2016.07.08
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Compositions and methods are provided relating to rotavirus serotypes and antibodies that bind to human rotavirus and modifications thereto which enhance the immunogenicity of the rotavirus protein for vaccine development with respect to the generation of a neutralizing immune response. Further disclosed are methods of using the antibodies for treating a rotavirus-mediated disease in a subject.