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Methods and compositions for detection of microbial contaminants in peritoneal dialysis solutions
专利权人:
发明人:
Leo Martis,Mehul Patel,Joseph A. Giertych,James W. Mongoven,Jacqueline A. Kunzier,William F. Owen
申请号:
US13974872
公开号:
US08859222B2
申请日:
2013.08.23
申请国别(地区):
US
年份:
2014
代理人:
摘要:
Methods and compositions for detection of microbial contaminants in peritoneal dialysis solutions are provided. A novel cause of aseptic peritonitis is provided—aseptic peritonitis associated with gram positive microbial contamination of a dialysis solution. Peptidoglycan is a major component of a gram positive bacterial cell wall and thus can serve as a marker for gram positive bacteria. In this regard, testing for peptidoglycans can be utilized to effectively prevent peritonitis in patients that use the peritoneal dialysis solutions, such as peritoneal dialysis solutions that contain a glucose polymer including an icodextrin and the like.
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